PQQ Supplement - 20mg, 60 Capsules (Pyrroloquinoline Quinone) Promotes Mitochondria ATP Coenzyme Levels, Energy Optimizer and Sleep Support (Non-GMO, Gluten Free, Vegan Safe) by Double Wood

It does work and I highly recommend it. Also have shown to Neurologist whom has been positive reading the ingredients.

I have been using PQQ for energy/mitochondria for at least 2 decades and have tried many brands. A lot of them just didn't work well. I stuck with a good brand for years despite its being pricey because it worked. I use PQQ along with NAC and CoQ10 or energy, mood, and overall well-being. It's a combo I would never want to be without. Recently I have found DOUBLE WOOD PQQ. It works! In fact, it works great! It works as well as the more pricey brand at a much more affordable price. I will stick with them as long as they stay in business. I will be 80 this year and everyone asks for my energy/attitude secret, even people 1/2 my age. Now when I share my secret, I recommend Double Wood brand!

Very good

Product is as advertised. I have been using this supplement for several months and notice a difference

so far so good!

The science so far backs up the use of PQQ for mitochondrial biogenesis.The unknown is whether mito biogenesis triggered by PGC-1 alpha reduces the abundance of mutant mtDNA and thus delays sarcopenia. One theory supporting that supposes that having more mitochondria reduces the oxidative load on each mitochondria, AND that the damage done by oxidation increases more-than-linearly with oxidative load.It is possible that the newly-made mtDNA is even more-likely to be mutant; or that mutant mtDNA will be triggered to reproduce in the same proportion as normal mtDNA, which would favor mutant mtDNA because deletion-mutants are shorter and hence reproduce faster. Certainly each turnover increases the chance for a de novo mutation. Whether PQQ can delay sarcopenia depends on whether the mitobiogenesis favors wild-type mtDNA. Similarly, the increase in autophagy that PQQ induces is also a question mark; we need to know whether this autophagy is random, or favors the destruction of mutant mitochondria.I didn't /feel/ any noticeable change while using PQQ, but I didn't expect to. I only wanted it to promote mitochondrial biogenesis, in order to spread the oxidative load across more mitochondria, thus hopefully reducing the average amount of mtDNA damage. As long as I believe that's plausible, I'd like to keep taking it. But I don't expect to be able to observe noticeable results from that for another 20 years.

The product is good price , just not sure the ingredients is really enough for what it claimed

A great anti-oxidant